GWAS-related meQTLs across different cancer types

We identified 2,214,458 meQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).



e.g., "BLCA"
e.g., "rs10000012"
e.g., "CTBP1"
e.g., "cg02980000"
Cancer type
QTL type
tagSNP
LD
SNP ID
SNP position (hg19)
alleles
probe
Gene position (hg19)
Gene
Beta
t-stat
r
p-value
Traits
BLCA cis rs829661 0.793 rs7572318 chr2:30808845 T/C cg17749961 chr2:30669863 LCLAT1 0.54 6.13 0.3 2.26E-9 Midgestational circulating levels of PBDEs (fetal genetic effect);
BLCA cis rs6951245 0.872 rs76713558 chr7:1095866 A/G cg20603222 chr7:1096387 C7orf50;GPR146 -0.51 -6.57 -0.32 1.68E-10 C-reactive protein levels or total cholesterol levels (pleiotropy);
BLCA cis rs7666738 0.83 rs7689495 chr4:98920152 T/C cg05340658 chr4:99064831 C4orf37 0.75 13.19 0.56 5.54E-33 Colonoscopy-negative controls vs population controls;
BLCA cis rs1784581 0.532 rs7767219 chr6:162423088 T/C cg17173639 chr6:162384350 PARK2 0.44 7.85 0.37 4.21E-14 Itch intensity from mosquito bite;
BLCA cis rs1215050 0.765 rs783947 chr4:99012943 T/C cg05340658 chr4:99064831 C4orf37 -0.56 -9.11 -0.42 4.77E-18 Waist-to-hip ratio adjusted for body mass index;
BLCA cis rs10870270 1 rs7898755 chr10:133777122 G/A cg26149184 chr10:133730230 NA 0.51 8.04 0.38 1.16E-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals;
BLCA cis rs11229555 0.598 rs7930623 chr11:58197641 A/G cg15696309 chr11:58395628 NA -0.52 -6.47 -0.31 3.07E-10 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease;
BLCA cis rs72945132 0.882 rs7935969 chr11:70194175 G/A cg14191688 chr11:70257035 CTTN 0.42 7.05 0.34 8.52E-12 Coronary artery disease;
BLCA cis rs7312774 0.748 rs7966019 chr12:107297502 G/T cg16260113 chr12:107380972 MTERFD3 0.73 7.21 0.35 2.96E-12 Severe influenza A (H1N1) infection;
BLCA cis rs798554 0.959 rs798556 chr7:2759002 C/A cg04166393 chr7:2884313 GNA12 0.56 7.93 0.38 2.54E-14 Height;
BLCA cis rs11148252 0.553 rs7999849 chr13:53249414 A/G cg02158880 chr13:53174818 NA 0.59 10.6 0.48 3.62E-23 Lewy body disease;
BLCA cis rs951366 0.844 rs823096 chr1:205679887 G/T cg14159672 chr1:205819179 PM20D1 0.78 13.29 0.56 2.21E-33 Menarche (age at onset);
BLCA cis rs829661 0.739 rs829563 chr2:30695497 T/A cg17749961 chr2:30669863 LCLAT1 0.54 6.2 0.3 1.45E-9 Midgestational circulating levels of PBDEs (fetal genetic effect);
BLCA cis rs5760092 0.755 rs915589 chr22:24261004 C/T cg16132339 chr22:24313637 DDTL;DDT -0.52 -7.43 -0.36 7.09E-13 Urinary 1,3-butadiene metabolite levels in smokers;
BLCA cis rs4727027 0.933 rs917123 chr7:148848358 G/A cg23158103 chr7:148848205 ZNF398 -0.57 -12.37 -0.54 9.37E-30 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells;